Anti-STUB1/CHIP 兔多克隆抗体-泛素化相关-科普欣生物 Cookbio 抗体|仪器|耗材|试剂-武汉科普欣生物科技有限公司

Anti-STUB1/CHIP 兔多克隆抗体

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￥1900

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货号： K1341478-100

预测分子量： 35 kDa

观测分子量： 35 kDa

别名： Antigen NY-CO-7, CHIP, CLL associated antigen KW 8, HSPABP2, NY CO 7, SDCCAG7, STUB1, UBOX1, PP1131, Antigen NY CO 7, Carboxy terminus of Hsp70 interacting protein, C terminus of Hsp70-interacting protein

应用 | 种属

WB H,M,R

规格：

100 μL 50 μL

产品描述
应用
背景
储存条件
图像

产品信息

蛋白质全称	E3泛素连接酶CHIP
别名	Antigen NY-CO-7, CHIP, CLL associated antigen KW 8, HSPABP2, NY CO 7, SDCCAG7, STUB1, UBOX1, PP1131, Antigen NY CO 7, Carboxy terminus of Hsp70 interacting protein, C terminus of Hsp70-interacting protein
Uniprot ID	Q9WUD1
免疫原	KLH偶联的小鼠STUB1合成肽
抗体亚型	IgG
纯化方式	亲和纯化
预测分子量./观测分子量.	35 kDa / 35 kDa

应用

WB 免疫印迹

物种:人, 小鼠, 大鼠

稀释比:1: 1000-1: 3000

阳性样品:

背景

STUB1, also named as CHIP, SDCCAG7, UBOX1 and NY-CO-7, is a E3 ubiquitin-protein ligase which targets misfolded chaperone substrates towards proteasomal degradation. STUB1/CHIP modulates the activity of several chaperone complexes, including Hsp70, Hsc70 and Hsp90. It mediates transfer of non-canonical short ubiquitin chains to HSPA8 that have no effect on HSPA8 degradation. STUB1/CHIP mediates polyubiquitination of CYP3A4. CHIP/STUB1 strongly reduced keratin aggregates through increased degradation of mutant K14.

储存条件

储存条件：-20℃下储存一年, 避免反复冻融.

储存缓冲液：含0.15% ProClin300防腐剂, 100 μg/mL牛血清白蛋白和50%甘油的磷酸盐缓冲液.

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