Anti-FBXO2 兔多克隆抗体-泛素化相关-科普欣生物 Cookbio 抗体|仪器|耗材|试剂-武汉科普欣生物科技有限公司

Anti-FBXO2 兔多克隆抗体

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￥1900

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货号： K1345051-100

预测分子量： 34 kDa

观测分子量： 40 kDa

亚细胞定位：细胞质, 微粒体膜

别名： F box only protein 2, F box protein 2, FBG1, Fbs1, FBX2, NFB42

应用 | 种属

WB R

IHC/IF M,R

ICC/IF H

规格：

100 μL 50 μL

产品描述
应用
背景
储存条件
图像

产品信息

蛋白质全称	F-box 蛋白2
别名	F box only protein 2, F box protein 2, FBG1, Fbs1, FBX2, NFB42
Uniprot ID	Q80UW2
免疫原	KLH偶联的小鼠FBXO2合成肽
抗体亚型	IgG
纯化方式	亲和纯化
亚细胞定位	细胞质, 微粒体膜
预测分子量./观测分子量.	34 kDa / 40 kDa

应用

WB 免疫印迹

物种:大鼠

稀释比:1: 800-1: 1500

阳性样品:

IHC/IF 免疫组织化学/免疫荧光

物种:小鼠, 大鼠

稀释比:1: 800-1: 2400

阳性样品:

ICC/IF 免疫细胞化学/免疫荧光

物种:人

稀释比:1: 200-1: 400

阳性样品:

背景

Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Involved in the endoplasmic reticulum-associated degradation pathway (ERAD) for misfolded lumenal proteins by recognizing and binding sugar chains on unfolded glycoproteins that are retrotranslocated into the cytosol and promoting their ubiquitination and subsequent degradation. Prevents formation of cytosolic aggregates of unfolded glycoproteins that have been retrotranslocated into the cytosol. Able to recognize and bind denatured glycoproteins, preferentially those of the high-mannose type.

储存条件

储存条件：-20℃下储存一年, 避免反复冻融.

储存缓冲液：含0.15% ProClin300防腐剂, 100 μg/mL牛血清白蛋白和50%甘油的磷酸盐缓冲液.

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