Anti-WWP1 兔多克隆抗体-泛素化相关-科普欣生物 Cookbio 抗体|仪器|耗材-武汉科普欣生物科技有限公司

热门搜索： CD3 Actin GFP

Anti-WWP1 兔多克隆抗体

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货号： K1346245-100

预测分子量： 105 kDa

观测分子量： 105 kDa

别名： AIP5, DKFZp434D2111, hSDRP1, Tiul1, WW domain containing protein 1, WWP1

应用 | 种属

WB M

规格：

100 μL

产品描述
应用
背景
储存条件
图像

产品信息

蛋白质全称	NEDD4样E3泛素连接酶WWP1
别名	AIP5, DKFZp434D2111, hSDRP1, Tiul1, WW domain containing protein 1, WWP1
Uniprot ID	Q8BZZ3
免疫原	小鼠WWP1重组蛋白
抗体亚型	IgG
纯化方式	亲和纯化
预测分子量./观测分子量.	105 kDa / 105 kDa

应用

WB 免疫印迹

物种:小鼠

稀释比:1: 2000-1: 3000

阳性样品:

背景

E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Ubiquitinates and promotes degradation of SMAD2 in response to TGF-beta signaling, which requires interaction with TGIF (By similarity). Ubiquitinates ERBB4 isoforms JM-A CYT-1 and JM-B CYT-1, KLF2, KLF5 and TP63 and promotes their proteasomal degradation. Ubiquitinates RNF11 without targeting it for degradation. Ubiquitinates and promotes degradation of TGFBR1; the ubiquitination is enhanced by SMAD7. Ubiquitinates SMAD6 and SMAD7.

储存条件

储存条件：储存条件在：-20℃下储存一年, 避免反复冻融.

储存缓冲液：含0.15% ProClin300防腐剂, 100 μg/mL牛血清白蛋白和50%甘油的磷酸盐缓冲液.

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