Anti-RBX1 兔多克隆抗体-泛素化相关-科普欣生物 Cookbio 抗体|仪器|耗材|试剂-武汉科普欣生物科技有限公司

Anti-RBX1 兔多克隆抗体

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￥1900

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货号： K1343245-100

预测分子量： 12 kDa

观测分子量： 13 kDa

别名： Protein ZYP, RBX1, Regulator of cullins 1, ring box 1, RING box protein 1, RING finger protein 75, RNF75, ROC1

应用 | 种属

WB M,R

规格：

100 μL 50 μL

产品描述
应用
背景
储存条件
图像

产品信息

蛋白质全称	E3泛素连接酶RBX1[剪切形式]
别名	Protein ZYP, RBX1, Regulator of cullins 1, ring box 1, RING box protein 1, RING finger protein 75, RNF75, ROC1
Uniprot ID	P62878
免疫原	小鼠ROC1重组蛋白
抗体亚型	IgG
纯化方式	亲和纯化
预测分子量./观测分子量.	12 kDa / 13 kDa

应用

WB 免疫印迹

物种:小鼠, 大鼠

稀释比:1: 300-1: 500

阳性样品:

背景

E3 ubiquitin ligase component of multiple cullin-RING-based E3 ubiquitin-protein ligase (CRLs) complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins, including proteins involved in cell cycle progression, signal transduction, transcription and transcription-coupled nucleotide excision repair . CRLs complexes and ARIH1 collaborate in tandem to mediate ubiquitination of target proteins, ARIH1 mediating addition of the first ubiquitin on CRLs targets . The functional specificity of the E3 ubiquitin-protein ligase complexes depends on the variable substrate recognition components . As a component of the CSA complex promotes the ubiquitination of ERCC6 resulting in proteasomal degradation.

储存条件

储存条件：-20℃下储存一年, 避免反复冻融.

储存缓冲液：含0.15% ProClin300防腐剂, 100 μg/mL牛血清白蛋白和50%甘油的磷酸盐缓冲液.

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