Recombinant Anti-MMP3 antibody (兔单克隆抗体)-肿瘤标志物,重组抗体-科普欣生物 Cookbio 抗体|仪器|耗材|试剂-武汉科普欣生物科技有限公司

Recombinant Anti-MMP3 antibody (兔单克隆抗体)

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￥1900

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货号： K5450609-100

预测分子量： 54 kDa

观测分子量： 37/50 kDa

亚细胞定位：细胞核, 细胞质, 分泌

别名： MMP3, CHDS6, MMP-3, SL-1, STMY STMY1, STR1, matrix metallopeptidase 3

应用 | 种属

WB H,M,R

IHC/IF H,M,R

规格：

100 μL 50 μL

产品描述
应用
背景
储存条件
图像

产品信息

蛋白质全称	基质金属蛋白酶-3
别名	MMP3, CHDS6, MMP-3, SL-1, STMY STMY1, STR1, matrix metallopeptidase 3
Uniprot ID	P08254
免疫原	人MMP3重组蛋白
抗体亚型	IgG
克隆号	SB682
纯化方式	亲和纯化
亚细胞定位	细胞核, 细胞质, 分泌
预测分子量./观测分子量.	54 kDa / 37/50 kDa

应用

WB 免疫印迹

物种:人, 小鼠, 大鼠

稀释比:1: 500-1: 1000

阳性样品:

IHC/IF 免疫组织化学/免疫荧光

物种:人, 小鼠, 大鼠

稀释比:1: 300-1: 1000

阳性样品:

背景

Metalloproteinase with a rather broad substrate specificity that can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates different molecules including growth factors, plasminogen or other matrix metalloproteinases such as MMP9. Once released into the extracellular matrix (ECM), the inactive pro-enzyme is activated by the plasmin cascade signaling pathway. Acts also intracellularly. For example, in dopaminergic neurons, gets activated by the serine protease HTRA2 upon stress and plays a pivotal role in DA neuronal degeneration by mediating microglial activation and alpha-synuclein/SNCA cleavage. In addition, plays a role in immune response and possesses antiviral activity against various viruses.

储存条件

储存条件：-20℃下储存一年, 避免反复冻融.

储存缓冲液：含0.15% ProClin300防腐剂, 100 μg/mL牛血清白蛋白和50%甘油的磷酸盐缓冲液.

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