Anti-Rb 兔多克隆抗体-细胞周期-科普欣生物 Cookbio 抗体|仪器|耗材|试剂-武汉科普欣生物科技有限公司

Anti-Rb 兔多克隆抗体

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￥1900

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货号： K1337347-100

预测分子量： 105 kDa

观测分子量： 105 kDa

别名： p110-RB1, pRb, Rb, pp105, Rb1, Rb-1, p105-Rb, OSRC, Prepro retinoblastoma associated protein

应用 | 种属

WB M

规格：

100 μL 50 μL

产品描述
应用
背景
储存条件
图像

产品信息

蛋白质全称	视网膜母细胞瘤相关蛋白
别名	p110-RB1, pRb, Rb, pp105, Rb1, Rb-1, p105-Rb, OSRC, Prepro retinoblastoma associated protein
Uniprot ID	P13405
免疫原	小鼠Rb重组蛋白
抗体亚型	IgG
纯化方式	亲和纯化
预测分子量./观测分子量.	105 kDa / 105 kDa

应用

WB 免疫印迹

物种:小鼠

稀释比:1: 300-1: 600

阳性样品:

背景

RB1, also named as pp110, pRb and p105 Rb, belongs to the retinoblastoma protein (RB) family. It is a key regulator of entry into cell division that acts as a tumor suppressor. RB1 acts as a transcription repressor of E2F1 target genes.Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. In case of viral infections, interactions with SV40 large T antigen, HPV E7 protein or adenovirus E1A protein induce the disassembly of RB1-E2F1 complex thereby disrupting RB1's activity. This antibody is a rabbit polyclonal antibody raised against residues near the C terminus of human RB1.

储存条件

储存条件：-20℃下储存一年, 避免反复冻融.

储存缓冲液：含0.15% ProClin300防腐剂, 100 μg/mL牛血清白蛋白和50%甘油的磷酸盐缓冲液.

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