| 蛋白质全称 | 溴脱氧尿嘧啶核苷 |
|---|---|
| 别名 | Bromodeoxyuridine,Bromodeoxyuridine,5-Bromo-2′-deoxyuridine; 5-BrdU,Proliferation Marker; 5-Bromo-2-deoxyUridine |
| Uniprot ID | None |
| 免疫原 | KLH偶联的小鼠BrdU合成肽 |
| 抗体亚型 | IgG1, κ |
| 克隆号 | 4B6C12 |
| 纯化方式 | 亲和纯化 |
| 亚细胞定位 | 细胞核 |
Bromodeoxyuridine (5-bromo-2'-deoxyuridine, BrdU, BUdR, BrdUrd) is a synthetic nucleoside that is an analog of thymidine. It can be incorporated into the newly synthesized DNA of replicating cells (during the S phase of the cell cycle), substituting for thymidine during DNA replication. As such, BrdU is used for birth dating and monitoring cell proliferation. BrdU is a toxic and mutagenic substance. It triggers cell death, the formation of teratomas, alters DNA stability, lengthens the cell cycle, and has mitogenic, transcriptional and translational effects on cells that incorporate it.
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