Lps,TLR4, ARMD10, CD284, TLR-4, TOLL, toll like receptor 4
Uniprot ID
Q9QUK6
免疫原
KLH偶联的小鼠TLR4合成肽
纯化方式
亲和纯化
预测分子量./观测分子量.
95 kDa /
95 kDa
应用
WB 免疫印迹
物种:人, 小鼠, 大鼠
稀释比:1: 500-1: 1000
阳性样品:
背景
TLR4 is a transmembrane protein, member of the toll-like receptor family, which belongs to the pattern recognition receptor (PRR) family. Its activation leads to an intracellular signaling pathway NF-κB and inflammatory cytokine production which is responsible for activating the innate immune system.It is most well known for recognizinglipopolysaccharide (LPS), a component present in many Gram-negative bacteria (e.g. Neisseria spp.) and selectGram-positive bacteria. Its ligands also include several viral proteins, polysaccharide, and a variety of endogenous proteins such as low-density lipoprotein, beta-defensins, and heat shock protein.