Anti-CREBBP 兔多克隆抗体-组蛋白相关-科普欣生物 Cookbio 抗体|仪器|耗材|试剂-武汉科普欣生物科技有限公司

Anti-CREBBP 兔多克隆抗体

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￥1900

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货号： K1346554-100

预测分子量： 265 kDa

观测分子量： 300 kDa

别名： CBP, CREB binding protein, CREBBP, KAT3A, RSTS

应用 | 种属

WB H,M,R

规格：

100 μL 50 μL

产品描述
应用
背景
储存条件
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产品信息

蛋白质全称	组蛋白乙酰转移酶CREBBP
别名	CBP, CREB binding protein, CREBBP, KAT3A, RSTS
Uniprot ID	P45481
免疫原	KLH偶联的小鼠CREBBP合成肽
抗体亚型	IgG
纯化方式	亲和纯化
预测分子量./观测分子量.	265 kDa / 300 kDa

应用

WB 免疫印迹

物种:人, 小鼠, 大鼠

稀释比:1: 300-1: 400

阳性样品:

背景

Acetylates histones, giving a specific tag for transcriptional activation (By similarity). Also acetylates non-histone proteins, like DDX21, FBL, IRF2, MAFG, NCOA3, POLR1E/PAF53 and FOXO1 Binds specifically to phosphorylated CREB and enhances its transcriptional activity toward cAMP-responsive genes (By similarity). Acts as a coactivator of ALX1 (By similarity). Acts as a circadian transcriptional coactivator which enhances the activity of the circadian transcriptional activators: NPAS2-ARNTL/BMAL1 and CLOCK-ARNTL/BMAL1 heterodimers (By similarity). Acetylates PCNA; acetylation promotes removal of chromatin-bound PCNA and its degradation during nucleotide excision repair (NER)

储存条件

储存条件：-20℃下储存一年, 避免反复冻融.

储存缓冲液：含0.15% ProClin300防腐剂, 100 μg/mL牛血清白蛋白和50%甘油的磷酸盐缓冲液.

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