Anti-MOCS3 兔多克隆抗体-能量代谢-科普欣生物 Cookbio 抗体|仪器|耗材|试剂-武汉科普欣生物科技有限公司

Anti-MOCS3 兔多克隆抗体

咨询

￥1900

加入对比

货号： K1342720-100

预测分子量： 49 kDa

观测分子量： 65 kDa

别名： MOCS3, UBA4, Sulfurtransferase MOCS3, Adenylyltransferase MOCS3

应用 | 种属

WB H,M,R

规格：

100 μL 50 μL

产品描述
应用
背景
储存条件
图像

产品信息

蛋白质全称	腺苷酸转移酶与硫转移酶MOCS3
别名	MOCS3, UBA4, Sulfurtransferase MOCS3, Adenylyltransferase MOCS3
Uniprot ID	A2BDX3
免疫原	小鼠MOCS3重组蛋白
抗体亚型	IgG
纯化方式	亲和纯化
预测分子量./观测分子量.	49 kDa / 65 kDa

应用

WB 免疫印迹

物种:人, 小鼠，大鼠

稀释比:1: 2000-1: 4000

阳性样品:

背景

Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (-COSH) of their C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1 and MOCS2A. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor; NFS1 probably acting as a sulfur donor for thiocarboxylation reactions.

储存条件

储存条件：储存条件在：-20℃下储存一年, 避免反复冻融.

储存缓冲液：含0.15% ProClin300防腐剂, 100 μg/mL牛血清白蛋白和50%甘油的磷酸盐缓冲液.

图像