Anti-CBX2 兔多克隆抗体-胚胎发育,染色质结合蛋白-科普欣生物 Cookbio 抗体|仪器|耗材|试剂-武汉科普欣生物科技有限公司

Anti-CBX2 兔多克隆抗体

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￥1900

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货号： K1336039-100

预测分子量： 55 kDa

观测分子量： 55 kDa

别名： M33, Modifier 3 protein, Cbx2, CDCA6, MOD2, SRXY5, Polycomb

应用 | 种属

WB H,M,R

规格：

100 μL 50 μL

产品描述
应用
背景
储存条件
图像

产品信息

蛋白质全称	染色盒同源蛋白2
别名	M33, Modifier 3 protein, Cbx2, CDCA6, MOD2, SRXY5, Polycomb
Uniprot ID	P30658
免疫原	KLH偶联的小鼠CBX2合成肽
抗体亚型	IgG
纯化方式	亲和纯化
预测分子量./观测分子量.	55 kDa / 55 kDa

应用

WB 免疫印迹

物种:人, 小鼠, 大鼠

稀释比:1: 500-1: 1000

阳性样品:

背景

Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development . PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility . Binds to histone H3 trimethylated at 'Lys-9' (H3K9me3) or at 'Lys-27' (H3K27me3) . Plays a role in the lineage differentiation of the germ layers in embryonic development . Involved in sexual development, acting as activator of NR5A1 expression .

储存条件

储存条件：储存条件在：-20℃下储存一年, 避免反复冻融.

储存缓冲液：含0.15% ProClin300防腐剂, 100 μg/mL牛血清白蛋白和50%甘油的磷酸盐缓冲液.

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