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Anti-TORC1 兔多克隆抗体
¥1900
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货号: K1333000-100
预测分子量: 67 kDa
观测分子量: 78 kDa
别名: Mucoepidermoid carcinoma translocated protein 1 homolog, TORC-1, Transducer of CREB protein 1, Crtc1, Kiaa0616, Mect1, Torc1, CRTC1, MECT1, TORC1, WAMTP1, CREB regulated transcription coactivator 1, MAML2, Mam-2
应用 | 种属
WB M,R
规格:
产品信息
蛋白质全称 CREB调节转录共激活因子1
别名 Mucoepidermoid carcinoma translocated protein 1 homolog, TORC-1, Transducer of CREB protein 1, Crtc1, Kiaa0616, Mect1, Torc1, CRTC1, MECT1, TORC1, WAMTP1, CREB regulated transcription coactivator 1, MAML2, Mam-2
Uniprot ID Q68ED7
免疫原 KLH偶联的小鼠TORC1合成肽
抗体亚型 IgG
纯化方式 亲和纯化
预测分子量./观测分子量. 67 kDa / 78 kDa
应用
WB 免疫印迹
物种:小鼠, 大鼠
稀释比:1: 500-1: 1000
阳性样品:
背景
CRTC1, also named as MECT1, TORC1, and WAMTP1, belongs to the TORC family. It is a transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. CRTC1 acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. It enhances the interaction of CREB1 with TAF4. CRTC1 regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. It is a potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells.
储存条件
储存条件:储存条件在:-20℃下储存一年, 避免反复冻融.
储存缓冲液:含0.15% ProClin300防腐剂, 100 μg/mL牛血清白蛋白和50%甘油的磷酸盐缓冲液.
图像
TORC1_d1000_WB

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