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Recombinant Anti-NOX2/gp91phox antibody (兔单克隆抗体)
¥1900
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货号: K5457086-100
预测分子量: 65 kDa
观测分子量: 65 kDa
别名: CGD91-phox, Cytochrome b(558) subunit beta, Cytochrome b558 subunit beta, Heme-binding membrane glycoprotein gp91phox, Neutrophil cytochrome b 91 kDa polypeptide, gp91-1, gp91-phox, p22 phagocyte B-cytochrome, Cybb, Cgd, CYBB, AMCBX2, GP91-PHOX, NOX2
应用 | 种属
WB H,M,R
规格:
产品信息
蛋白质全称 细胞色素b-245重链
别名 CGD91-phox, Cytochrome b(558) subunit beta, Cytochrome b558 subunit beta, Heme-binding membrane glycoprotein gp91phox, Neutrophil cytochrome b 91 kDa polypeptide, gp91-1, gp91-phox, p22 phagocyte B-cytochrome, Cybb, Cgd, CYBB, AMCBX2, GP91-PHOX, NOX2
Uniprot ID P04839
免疫原 KLH偶联的人gp91phox合成肽
抗体亚型 IgG
克隆号 SB490
纯化方式 亲和纯化
预测分子量./观测分子量. 65 kDa / 65 kDa
应用
WB 免疫印迹
物种:人, 小鼠, 大鼠
稀释比:1: 1000-1: 2000
阳性样品:
背景
NOX2/gp91phox is a critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior. It also functions as a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes. It participates in the regulation of cellular pH and is blocked by zinc. Defects in CYBB are a cause of X-linked chronic granulomatous disease (X-CGD). X-CGD is characterized by the failure of activated phagocytes to generate superoxide.
储存条件
储存条件:储存条件在:-20℃下储存一年, 避免反复冻融.
储存缓冲液:含0.15% ProClin300防腐剂, 100 μg/mL牛血清白蛋白和50%甘油的磷酸盐缓冲液.
图像
NOX2_WB

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