Anti-PDK4 兔多克隆抗体-能量代谢-科普欣生物 Cookbio 抗体|仪器|耗材-武汉科普欣生物科技有限公司

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Anti-PDK4 兔多克隆抗体

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￥1900

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货号： K1341361-100

预测分子量： 47 kDa

观测分子量： 43 kDa

别名： Pyruvate dehydrogenase kinase isoform 4, Pdk4, Pyruvate dehydrogenase kinase 4

应用 | 种属

WB M

规格：

100 μL

产品描述
应用
背景
储存条件
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产品信息

蛋白质全称	线粒体丙酮酸脱氢酶激酶同工酶4
别名	Pyruvate dehydrogenase kinase isoform 4, Pdk4, Pyruvate dehydrogenase kinase 4
Uniprot ID	O70571
免疫原	KLH偶联的小鼠PDK4合成肽
抗体亚型	IgG
纯化方式	亲和纯化
预测分子量./观测分子量.	47 kDa / 43 kDa

应用

WB 免疫印迹

物种:小鼠

稀释比:1: 1000-1: 3000

阳性样品:

背景

Pyruvate dehydrogenase kinase isoform4 (PDK4) is also named as PDHK4 and belongs to the PDK/BCKDK protein kinase family. It is upregulated by starvation in many tissues of the body during starvation. This causes inactivation of the pyruvate dehydrogenase complex which blocks pyruvate oxidation and conserves lactate and alanine for gluconeogenesis. Enhanced PDK4 expression may be caused by the increase in free fatty acids that occurs during starvation. Free fatty acids can activate peroxisome proliferator-activated receptor α (PPARα), and activation of PPARα can promote PDK4 expression.

储存条件

储存条件：储存条件在：-20℃下储存一年, 避免反复冻融.

储存缓冲液：含0.15% ProClin300防腐剂, 100 μg/mL牛血清白蛋白和50%甘油的磷酸盐缓冲液.

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