Anti-MPRIP 兔多克隆抗体-细胞骨架-科普欣生物 Cookbio 抗体|仪器|耗材|试剂-武汉科普欣生物科技有限公司

Anti-MPRIP 兔多克隆抗体

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￥1900

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货号： K1334974-100

预测分子量： 116 kDa

观测分子量： 130 kDa

别名： Rho-interacting protein 3, RIP3, p116Rip, Kiaa0864, Rhoip3, Mrip, RP23-180B18.4, p116 Rho-interacting protein

应用 | 种属

WB H,M,R

规格：

100 μL 50 μL

产品描述
应用
背景
储存条件
图像

产品信息

蛋白质全称	肌球蛋白磷酸酶Rho相互作用蛋白
别名	Rho-interacting protein 3, RIP3, p116Rip, Kiaa0864, Rhoip3, Mrip, RP23-180B18.4, p116 Rho-interacting protein
Uniprot ID	P97434
免疫原	小鼠 MPRIP重组蛋白
抗体亚型	IgG
纯化方式	亲和纯化
预测分子量./观测分子量.	116 kDa / 130 kDa

应用

WB 免疫印迹

物种:人, 小鼠, 大鼠

稀释比:1: 500-1: 1000

阳性样品:

背景

MPRIP, also named as KIAA0864, MRIP, RHOIP3 and p116Rip, is required for the regulation of the actin cytoskeleton by RhoA and ROCK1. MRPIP targets myosin phosphatase to the actin cytoskeleton. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells. The antibody recognizes the C-term of isoform2 and isoform3 of MPRIP.

储存条件

储存条件：-20℃下储存一年, 避免反复冻融.

储存缓冲液：含0.15% ProClin300防腐剂, 100 μg/mL牛血清白蛋白和50%甘油的磷酸盐缓冲液.

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