Anti-AP endonuclease 2 兔多克隆抗体-DNA损伤修复-科普欣生物 Cookbio 抗体|仪器|耗材|试剂-武汉科普欣生物科技有限公司

Anti-AP endonuclease 2 兔多克隆抗体

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￥1900

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货号： K1344562-100

预测分子量： 57 kDa

观测分子量： 57 kDa

别名： Ape2, APEXL2, APEX2, APEX nuclease 2, AP endonuclease 2, XTH2

应用 | 种属

WB H,R

规格：

100 μL 50 μL

产品描述
应用
背景
储存条件
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产品信息

蛋白质全称	DNA（无嘌呤/无嘧啶位点）核酸内切酶2
别名	Ape2, APEXL2, APEX2, APEX nuclease 2, AP endonuclease 2, XTH2
Uniprot ID	Q68G58
免疫原	KLH偶联的小鼠AP endonuclease 2合成肽
抗体亚型	IgG
纯化方式	亲和纯化
预测分子量./观测分子量.	57 kDa / 57 kDa

应用

WB 免疫印迹

物种:人, 大鼠

稀释比:1: 1000-1: 2000

阳性样品:

背景

Functions as a weak apurinic/apyrimidinic (AP) endodeoxyribonuclease in the DNA base excision repair (BER) pathway of DNA lesions induced by oxidative and alkylating agents.Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.Also displays double-stranded DNA 3'-5' exonuclease, 3'-phosphodiesterase activities. Shows robust 3'-5' exonuclease activity on 3'-recessed heteroduplex DNA and is able to remove mismatched nucleotides preferentially .

储存条件

储存条件：-20℃下储存一年, 避免反复冻融.

储存缓冲液：含0.15% ProClin300防腐剂, 100 μg/mL牛血清白蛋白和50%甘油的磷酸盐缓冲液.

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