Anti-Phospho-YAP1(S127) 兔多克隆抗体-修饰抗体,原癌/抑癌基因蛋白,其它-科普欣生物 Cookbio 抗体|仪器|耗材|试剂-武汉科普欣生物科技有限公司

Anti-Phospho-YAP1(S127) 兔多克隆抗体

咨询

￥1900

加入对比

货号： K1342180-100

预测分子量： 48-54 kDa

观测分子量： 78 kDa

别名： 65 kDa Yes associated protein, YAP, YAP1, YAP2, YAP65, YKI, Yorkie homolog, P-YAP1

应用 | 种属

WB H,M,R

规格：

100 μL 50 μL

产品描述
应用
背景
储存条件
图像

产品信息

蛋白质全称	转录共激活因子YAP1
别名	65 kDa Yes associated protein, YAP, YAP1, YAP2, YAP65, YKI, Yorkie homolog, P-YAP1
Uniprot ID	P46937
免疫原	KLH偶联的人YAP1(S127)合成磷酸肽
抗体亚型	IgG
纯化方式	亲和纯化
预测分子量./观测分子量.	48-54 kDa / 78 kDa

应用

WB 免疫印迹

物种:人, 小鼠, 大鼠

稀释比:1: 300-1: 500

阳性样品:

背景

Yes-associated protein 1 (YAP1) is a transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ.

储存条件

储存条件：储存条件在：-20℃下储存一年, 避免反复冻融.

储存缓冲液：含0.15% ProClin300防腐剂, 100 μg/mL牛血清白蛋白和50%甘油的磷酸盐缓冲液.

图像