Anti-Pleckstrin 兔多克隆抗体-钙信号通路-科普欣生物 Cookbio 抗体|仪器|耗材|试剂-武汉科普欣生物科技有限公司

Anti-Pleckstrin 兔多克隆抗体

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￥1900

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货号： K1341025-100

预测分子量： 40 kDa

观测分子量： 40 kDa

别名： P47, Platelet 47 kDa protein, PLEK, Platelet P47, Platelet and leukocyte C kinase substrate

应用 | 种属

WB H,M,R

规格：

100 μL 50 μL

产品描述
应用
背景
储存条件
图像

产品信息

蛋白质全称	血小板-白细胞激酶
别名	P47, Platelet 47 kDa protein, PLEK, Platelet P47, Platelet and leukocyte C kinase substrate
Uniprot ID	Q9JHK5
免疫原	KLH偶联的小鼠Pleckstrin合成肽
抗体亚型	IgG
纯化方式	亲和纯化
预测分子量./观测分子量.	40 kDa / 40 kDa

应用

WB 免疫印迹

物种:人, 小鼠, 大鼠

稀释比:1: 300-1: 600

阳性样品:

背景

PLEK (pleckstrin; also known as p47) was originally identified as the major PKC substrate in platelets and later is found to be expressed in all cells of the hemopoietic system. Through two pleckstrin homology (PH) domains at its N and C termini, PLEK may interact with various protein and/or lipid ligands and serve as an intracellular adaptor/targeting protein. Predominantly cytosolic in unstimulated cells, PLEK would undergo transient redistribution to phagosomal membrane in response to stimuli. PLEK has been found to be hyperphosphorylated in diabetic mononuclear phagocytes and promote proinflammatory cytokine secretion in diabetes.

储存条件

储存条件：储存条件在：-20℃下储存一年, 避免反复冻融.

储存缓冲液：含0.15% ProClin300防腐剂, 100 μg/mL牛血清白蛋白和50%甘油的磷酸盐缓冲液.

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