Anti-GPR161 兔多克隆抗体-G蛋白偶联受体-科普欣生物 Cookbio 抗体|仪器|耗材|试剂-武汉科普欣生物科技有限公司

Anti-GPR161 兔多克隆抗体

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￥1900

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货号： K1334263-100

预测分子量： 60 kDa

观测分子量： 65 kDa

别名： Gpr161, Gm208, RE2, G protein coupled receptor RE2

应用 | 种属

WB M,R

规格：

100 μL 50 μL

产品描述
应用
背景
储存条件
图像

产品信息

蛋白质全称	G蛋白偶联受体161
别名	Gpr161, Gm208, RE2, G protein coupled receptor RE2
Uniprot ID	B2RPY5
免疫原	KLH偶联的小鼠GPR161合成肽
抗体亚型	IgG
纯化方式	亲和纯化
预测分子量./观测分子量.	60 kDa / 65 kDa

应用

WB 免疫印迹

物种:小鼠, 大鼠

稀释比:1: 500-1: 1000

阳性样品:

背景

GPR161 (also known as RE2) is an orphan G protein-coupled receptor and plays important roles in the Hh pathway. In the absence of Hh signals, GPR161 localizes to primary cilia and keeps the downstream GLI transcription factors in their repressor forms . Ciliary localization of GPR161 requires TULP3 and the IFT-A complex. In presence of SHH, GPR161 is removed from primary cilia and is internalized into recycling endosomes, preventing its activity and allowing activation of the Shh signaling.

储存条件

储存条件：储存条件在：-20℃下储存一年, 避免反复冻融.

储存缓冲液：含0.15% ProClin300防腐剂, 100 μg/mL牛血清白蛋白和50%甘油的磷酸盐缓冲液.

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