| 蛋白质全称 | 5-羟色胺受体1A |
|---|---|
| 别名 | Htr1a, HTR1A, 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled, 5-HT-1A, 5-HT1A, 5HT1a, ADRB2RL1, ADRBRL1, G-21, PFMCD, 5HT1A Receptor, Serotonin receptor 1A |
| Uniprot ID | Q64264 |
| 免疫原 | KLH偶联的小鼠5HT1A Receptor合成肽 |
| 抗体亚型 | IgG |
| 纯化方式 | 亲和纯化 |
| 预测分子量./观测分子量. | 46 kDa / 46 kDa |
G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second messenger system that regulates the release of Ca(2+) ions from intracellular stores.
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