Anti-MMP3 小鼠单克隆抗体-肿瘤标志物-科普欣生物 Cookbio 抗体|仪器|耗材-武汉科普欣生物科技有限公司

热门搜索： CD3 Actin GFP

Anti-MMP3 小鼠单克隆抗体

咨询

￥1900

加入对比

货号： K236393-100

预测分子量： 54 kDa

观测分子量： 47 kDa

别名： MMP3, CHDS6, MMP-3, SL-1, STMY STMY1, STR1, matrix metallopeptidase 3

应用 | 种属

WB H,M,R

规格：

100 μL

产品描述
应用
背景
储存条件
图像

产品信息

蛋白质全称	基质金属蛋白酶-3
别名	MMP3, CHDS6, MMP-3, SL-1, STMY STMY1, STR1, matrix metallopeptidase 3
Uniprot ID	P28862
免疫原	小鼠MMP3重组蛋白
抗体亚型	IgG1, κ
克隆号	2C12G6
纯化方式	亲和纯化
预测分子量./观测分子量.	54 kDa / 47 kDa

应用

WB 免疫印迹

物种:人, 小鼠, 大鼠

稀释比:1: 500-1: 1000

阳性样品:

背景

Metalloproteinase with a rather broad substrate specificity that can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates different molecules including growth factors, plasminogen or other matrix metalloproteinases such as MMP9. Once released into the extracellular matrix (ECM), the inactive pro-enzyme is activated by the plasmin cascade signaling pathway. Acts also intracellularly. For example, in dopaminergic neurons, gets activated by the serine protease HTRA2 upon stress and plays a pivotal role in DA neuronal degeneration by mediating microglial activation and alpha-synuclein/SNCA cleavage. In addition, plays a role in immune response and possesses antiviral activity against various viruses.

储存条件

储存条件：储存条件在：-20℃下储存一年, 避免反复冻融.

储存缓冲液：含0.15% ProClin300防腐剂, 100 μg/mL牛血清白蛋白和50%甘油的磷酸盐缓冲液.

图像