Anti-PKR 兔多克隆抗体-其它-科普欣生物 Cookbio 抗体|仪器|耗材-武汉科普欣生物科技有限公司

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Anti-PKR 兔多克隆抗体

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￥1900

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货号： K1333291-100

预测分子量： 58 kDa

观测分子量： 62 kDa

别名： eIF-2A protein kinase 2, Interferon-inducible RNA-dependent protein kinase, P1/eIF-2A protein kinase, Protein kinase R, Pkr, Eif2ak2, Prkr, p68 kinase, Tik, Serine/threonine-protein kinase TIK, Tyrosine-protein kinase EIF2AK2

应用 | 种属

WB M

规格：

100 μL

产品描述
应用
背景
储存条件
图像

产品信息

蛋白质全称	干扰素诱导双链RNA激活蛋白激酶
别名	eIF-2A protein kinase 2, Interferon-inducible RNA-dependent protein kinase, P1/eIF-2A protein kinase, Protein kinase R, Pkr, Eif2ak2, Prkr, p68 kinase, Tik, Serine/threonine-protein kinase TIK, Tyrosine-protein kinase EIF2AK2
Uniprot ID	Q03963
免疫原	小鼠PKR重组蛋白
抗体亚型	IgG
纯化方式	亲和纯化
预测分子量./观测分子量.	58 kDa / 62 kDa

应用

WB 免疫印迹

物种:小鼠

稀释比:1: 500-1: 1000

阳性样品:

背景

PKR is an IFN-induced serine/threonine protein kinase consisting activated by dsRNA produced during viral infections, PKR plays a key role in IFN induced-innate antiviral response, virus-induced apoptosis, cell growth and differentiation. Upon activation, PKR gets autophosphorylated and catalyzes the phosphorylation of elF2 alpha subunit, which leads to an inhibition of protein synthesis. PKR induces apoptosis by up-regulating Fas expression and mediates FADD/Caspase-8 death signaling pathway.

储存条件

储存条件：储存条件在：-20℃下储存一年, 避免反复冻融.

储存缓冲液：含0.15% ProClin300防腐剂, 100 μg/mL牛血清白蛋白和50%甘油的磷酸盐缓冲液.

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