Anti-UPF3A 兔多克隆抗体-RNA加工-科普欣生物 Cookbio 抗体|仪器|耗材-武汉科普欣生物科技有限公司

热门搜索： CD3 Actin GFP

Anti-UPF3A 兔多克隆抗体

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￥1900

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货号： K1346224-100

预测分子量： 55 kDa

观测分子量： 55 kDa

别名： hUpf3, HUPF3A, RENT3A, UPF3, UPF3A

应用 | 种属

WB M

规格：

100 μL

产品描述
应用
背景
储存条件
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产品信息

蛋白质全称	无义转录调控因子3A
别名	hUpf3, HUPF3A, RENT3A, UPF3, UPF3A
Uniprot ID	Q9H1J1
免疫原	KLH偶联的人UPF3A合成肽
抗体亚型	IgG
纯化方式	亲和纯化
预测分子量./观测分子量.	55 kDa / 55 kDa

应用

WB 免疫印迹

物种:小鼠

稀释比:1: 500-1: 1000

阳性样品:

背景

Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by associating with the nuclear exon junction complex (EJC) and serving as link between the EJC core and NMD machinery. Recruits UPF2 at the cytoplasmic side of the nuclear envelope and the subsequent formation of an UPF1-UPF2-UPF3 surveillance complex (including UPF1 bound to release factors at the stalled ribosome) is believed to activate NMD. However, UPF3A is shown to be only marginally active in NMD as compared to UPF3B. Binds spliced mRNA upstream of exon-exon junctions. In vitro, weakly stimulates translation.

储存条件

储存条件：储存条件在：-20℃下储存一年, 避免反复冻融.

储存缓冲液：含0.15% ProClin300防腐剂, 100 μg/mL牛血清白蛋白和50%甘油的磷酸盐缓冲液.

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