Anti-PMP52 兔多克隆抗体-其它-科普欣生物 Cookbio 抗体|仪器|耗材|试剂-武汉科普欣生物科技有限公司

Anti-PMP52 兔多克隆抗体

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￥1900

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货号： K1344592-100

预测分子量： 19 kDa

观测分子量： 18 kDa

别名： Transmembrane protein 35A, PMP52, Tmem35a, NachoPeroxisomal membrane protein 52

应用 | 种属

WB M,R

规格：

100 μL 50 μL

产品描述
应用
背景
储存条件
图像

产品信息

蛋白质全称	新型乙酰胆碱受体伴侣蛋白
别名	Transmembrane protein 35A, PMP52, Tmem35a, NachoPeroxisomal membrane protein 52
Uniprot ID	Q9D328
免疫原	KLH偶联的小鼠PMP52合成肽
抗体亚型	IgG
纯化方式	亲和纯化
预测分子量./观测分子量.	19 kDa / 18 kDa

应用

WB 免疫印迹

物种:小鼠, 大鼠

稀释比:1: 300-1: 800

阳性样品:

背景

Molecular chaperone which mediates the proper assembly and functional expression of the nicotinic acetylcholine receptors (nAChRs) throughout the brain. Essential for the proper folding, assembly, function and surface trafficking of alpha-7 (CHRNA7), alpha-4-beta-2, alpha-3-beta-2 and alpha-3-beta-4 receptors. Stably associates with ribophorin-1 (RPN1) and ribophorin-2 (RPN2) (components of the oligosaccharyl transferase (OST) complex) and with calnexin (CANX), both of which are critical for NACHO-mediated effects on CHRNA7 assembly and function. Facilitates the proper folding and assembly of alpha-6-beta-2 and alpha-6-beta-2-beta-3 receptors and acts at early stages of the nAChRs subunit assembly.

储存条件

储存条件：-20℃下储存一年, 避免反复冻融.

储存缓冲液：含0.15% ProClin300防腐剂, 100 μg/mL牛血清白蛋白和50%甘油的磷酸盐缓冲液.

图像