Anti-TIA1 兔多克隆抗体-RNA加工-科普欣生物 Cookbio 抗体|仪器|耗材|试剂-武汉科普欣生物科技有限公司

Anti-TIA1 兔多克隆抗体

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￥1900

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货号： K1341175-100

预测分子量： 43 kDa

观测分子量： 43 kDa

别名： Nucleolysin TIA 1 isoform p40, p40 TIA 1, RNA binding protein TIA 1, TIA-1, TIA1, T-cell-restricted intracellular antigen-1, Tia

应用 | 种属

WB M,R

规格：

100 μL 50 μL

产品描述
应用
背景
储存条件
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产品信息

蛋白质全称	核溶素TIA-1
别名	Nucleolysin TIA 1 isoform p40, p40 TIA 1, RNA binding protein TIA 1, TIA-1, TIA1, T-cell-restricted intracellular antigen-1, Tia
Uniprot ID	P52912
免疫原	KLH偶联的小鼠TIA1合成肽
抗体亚型	IgG
纯化方式	亲和纯化
预测分子量./观测分子量.	43 kDa / 43 kDa

应用

WB 免疫印迹

物种:小鼠, 大鼠

稀释比:1: 300-1: 600

阳性样品:

背景

TIA1, also named as p40-TIA-1, is involved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3' untranslated regions (3' UTRs). It possesses nucleolytic activity against cytotoxic lymphocyte target cells. TIA1 may be involved in apoptosis. Two isoforms of this protein exist - 41kDa and 42kDa. one of these was a missense variant (P362L) in TIA1. Similar to the ALS-related disease proteins TDP-43, hnRNPA1, and FUS, TIA1 is an RNA-binding protein containing a prionlike LCD and assembles into membrane-less organelles, including SGs.

储存条件

储存条件：-20℃下储存一年, 避免反复冻融.

储存缓冲液：含0.15% ProClin300防腐剂, 100 μg/mL牛血清白蛋白和50%甘油的磷酸盐缓冲液.

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