Anti-IRSp53 兔多克隆抗体-细胞骨架,小G蛋白相关-科普欣生物 Cookbio 抗体|仪器|耗材|试剂-武汉科普欣生物科技有限公司

Anti-IRSp53 兔多克隆抗体

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￥1900

加入对比

货号： K1341289-100

预测分子量： 59 kDa

观测分子量： 53/59 kDa

别名： BAI associated protein 2, BAI1 associated protein 2, BAIAP2, BAP2, Fas ligand associated factor 3, FLAF3, Insulin receptor substrate p53, IRS 58, IRSp53, IRSp53/58, Protein BAP2

应用 | 种属

WB M,R

规格：

100 μL 50 μL

产品描述
应用
背景
储存条件
图像

产品信息

蛋白质全称	脑特异性血管生成抑制因子关联蛋白2
别名	BAI associated protein 2, BAI1 associated protein 2, BAIAP2, BAP2, Fas ligand associated factor 3, FLAF3, Insulin receptor substrate p53, IRS 58, IRSp53, IRSp53/58, Protein BAP2
Uniprot ID	Q8BKX1
免疫原	KLH偶联的小鼠IRSp53合成肽
抗体亚型	IgG
纯化方式	亲和纯化
预测分子量./观测分子量.	59 kDa / 53/59 kDa

应用

WB 免疫印迹

物种:小鼠, 大鼠

稀释比:1: 500-1: 1000

阳性样品:

背景

IRSp53 (also known as BAIAP2) is a multi-domain adaptor protein that originally identified as a 58/53-kDa substrate of insulin-receptor kinase in the hamster . As a BAI1-binding protein, IRSp53 plays an important role in linking between membrane and cytoskeleton in the process of neuronal growth . IRSp53 is necessary for Cdc42-mediated reorganization of the actin cytoskeleton and for Rac1-mediated membrane ruffling. Alternatively spliced isoforms of IRSp53 exist. IRSp53 has been implicated in several psychiatric disorders, including autism spectrum disorders (ASDs), schizophrenia, and attention deficit/hyperactivity disorder (ADHD).

储存条件

储存条件：-20℃下储存一年, 避免反复冻融.

储存缓冲液：含0.15% ProClin300防腐剂, 100 μg/mL牛血清白蛋白和50%甘油的磷酸盐缓冲液.

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