Anti-Perforin 兔多克隆抗体-细胞杀伤相关-科普欣生物 Cookbio 抗体|仪器|耗材|试剂-武汉科普欣生物科技有限公司

Anti-Perforin 兔多克隆抗体

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￥1900

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货号： K135829-100

预测分子量： 61 kDa

观测分子量： 70 kDa

别名： P1, Cytolysin, Lymphocyte pore-forming protein, PFP, PRF1, FLH2, HPLH2, MGC65093, Perforin 1, Perforin 1 precursor, Perforin 1 preforming protein, PGFL, PIGF, PIGF-2, PLGF, SHGC-10760

应用 | 种属

WB H,R

规格：

100 μL 50 μL

产品描述
应用
背景
储存条件
图像

产品信息

蛋白质全称	穿孔素1
别名	P1, Cytolysin, Lymphocyte pore-forming protein, PFP, PRF1, FLH2, HPLH2, MGC65093, Perforin 1, Perforin 1 precursor, Perforin 1 preforming protein, PGFL, PIGF, PIGF-2, PLGF, SHGC-10760
Uniprot ID	P14222
免疫原	KLH偶联的人Perforin合成肽
抗体亚型	IgG
纯化方式	亲和纯化
预测分子量./观测分子量.	61 kDa / 70 kDa

应用

WB 免疫印迹

物种:人, 大鼠

稀释比:1: 500-1: 1000

阳性样品:

背景

It is known to be a crucial effector molecule in cytolytic T lymphocyte and natural killer cell-mediated cytotoxicity. This protein has structural and functional similarities to complement component C9. Like C9, this protein creates transmembrane tubules and is capable of lysing nonspecifically a variety of target cells. Defects in PRF1 are the cause of familial hemophagocytic lymphohistiocytosis type 2 (FHL2), a rare and lethal autosomal recessive disorder of early childhood，which is characterized by immune dysregulation with hypercytokinemia and defective natural killer cell function.

储存条件

储存条件：-20℃下储存一年, 避免反复冻融.

储存缓冲液：含0.15% ProClin300防腐剂, 100 μg/mL牛血清白蛋白和50%甘油的磷酸盐缓冲液.

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