Anti-Cortactin 兔多克隆抗体-细胞骨架-科普欣生物 Cookbio 抗体|仪器|耗材|试剂-武汉科普欣生物科技有限公司

Anti-Cortactin 兔多克隆抗体

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￥1900

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货号： K135013-100

预测分子量： 61 kDa

观测分子量： 80 kDa

别名： Cttn, CTTN, EMS1, Cortactin, Amplaxin, Mammary tumor and squamous cell carcinoma associated, p80/85 src substrate, Src substrate cortactin, SRC8

应用 | 种属

WB H,M,R

规格：

100 μL 50 μL

产品描述
应用
背景
储存条件
图像

产品信息

蛋白质全称	Src 底物膜连接蛋白
别名	Cttn, CTTN, EMS1, Cortactin, Amplaxin, Mammary tumor and squamous cell carcinoma associated, p80/85 src substrate, Src substrate cortactin, SRC8
Uniprot ID	Q60598
免疫原	小鼠Cortactin重组蛋白
抗体亚型	IgG
纯化方式	亲和纯化
预测分子量./观测分子量.	61 kDa / 80 kDa

应用

WB 免疫印迹

物种:人, 小鼠, 大鼠

稀释比:1: 500-1: 1000

阳性样品:

背景

This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene.

储存条件

储存条件：-20℃下储存一年, 避免反复冻融.

储存缓冲液：含0.15% ProClin300防腐剂, 100 μg/mL牛血清白蛋白和50%甘油的磷酸盐缓冲液.

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