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Anti-Staufen/STAU1 兔多克隆抗体
¥1900
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货号: K1335772-100
预测分子量: 54 kDa
观测分子量: 54 kDa
别名: Stau1, Stau, staufen, Staufen RNA binding protein homolog 1, PPP1R150, FLJ25010, Staufen/STAU1
应用 | 种属
WB H,M
产品信息
蛋白质全称 双链RNA结合蛋白Staufen同源物1
别名 Stau1, Stau, staufen, Staufen RNA binding protein homolog 1, PPP1R150, FLJ25010, Staufen/STAU1
Uniprot ID Q9Z108
免疫原 小鼠Staufen/STAU1重组蛋白
抗体亚型 IgG
纯化方式 亲和纯化
预测分子量./观测分子量. 54 kDa / 54 kDa
应用
WB 免疫印迹
物种:人, 小鼠
稀释比:1: 500-1: 1000
阳性样品:
背景
Staufen1 (STAU1)-mediated mRNA decay (SMD) degrades translationally active mRNAs that bind the double-stranded (ds)RNA binding protein STAU1 within their 3'-untranslated regions (3'UTRs) [PMID:21307942]. STAU1 can binds to stem structures and protect Dvl2 mRNA from degradation by associating with the secondary structure in the U1 region which is located at 5′ position of second U stretch in the U2 region [PMID:17510634]. It has a role in specific positioning of mRNAs at given sites in the cell by cross-linking cytoskeletal and RNA components, and in stimulating their translation at the site.
储存条件
储存条件:-20℃下储存一年, 避免反复冻融.
储存缓冲液:含0.15% ProClin300防腐剂, 100 μg/mL牛血清白蛋白和50%甘油的磷酸盐缓冲液.
图像
STAU1_d1000_WB

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