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Recombinant Anti-CD19 antibody (兔重组单克隆抗体)
¥1900
加入对比
货号: K5450600-100
预测分子量: 60 kDa
观测分子量: 60-120 kDa
亚细胞定位: 细胞膜
别名: B lymphocyte antigen CD19, B4, CD19, CD19 molecule, Differentiation antigen CD19, T cell surface antigen Leu 12, CVID3
应用 | 种属
WB H,M
IHC/IF M
产品信息
蛋白质全称 B淋巴细胞抗原CD19
别名 B lymphocyte antigen CD19, B4, CD19, CD19 molecule, Differentiation antigen CD19, T cell surface antigen Leu 12, CVID3
Uniprot ID P25918
免疫原 小鼠CD19重组蛋白
抗体亚型 IgG
克隆号 SB673
纯化方式 亲和纯化
亚细胞定位 细胞膜
预测分子量./观测分子量. 60 kDa / 60-120 kDa
应用
WB 免疫印迹
物种:人, 小鼠
稀释比:1: 500-1: 2000
阳性样品:
IHC/IF 免疫组织化学/免疫荧光
物种:小鼠
稀释比:1: 400-1: 800
阳性样品:
背景
Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens. Activates signaling pathways that lead to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca(2+) stores. Is not required for early steps during B cell differentiation in the blood marrow. Required for normal differentiation of B-1 cells (By similarity). Required for normal B cell differentiation and proliferation in response to antigen challenges. Required for normal levels of serum immunoglobulins, and for production of high-affinity antibodies in response to antigen challenge.
储存条件
储存条件:储存条件在:-20℃下储存一年, 避免反复冻融.
储存缓冲液:含0.15% ProClin300防腐剂, 100 μg/mL牛血清白蛋白和50%甘油的磷酸盐缓冲液.
图像
CD19_WB

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