Anti-TRIM7 兔多克隆抗体-泛素化相关-科普欣生物 Cookbio 抗体|仪器|耗材|试剂-武汉科普欣生物科技有限公司

Anti-TRIM7 兔多克隆抗体

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￥1900

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货号： K1343788-100

预测分子量： 57 kDa

观测分子量： 57 kDa

别名： Glycogenin interacting protein, GNIP, RING finger protein 90, RNF90, TRIM7, tripartite motif containing 7

应用 | 种属

WB M

规格：

100 μL 50 μL

产品描述
应用
背景
储存条件
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产品信息

蛋白质全称	E3泛素连接酶TRIM7
别名	Glycogenin interacting protein, GNIP, RING finger protein 90, RNF90, TRIM7, tripartite motif containing 7
Uniprot ID	Q923T7
免疫原	KLH偶联的小鼠TRIM7合成肽
抗体亚型	IgG
纯化方式	亲和纯化
预测分子量./观测分子量.	57 kDa / 57 kDa

应用

WB 免疫印迹

物种:小鼠

稀释比:1: 300-1: 800

阳性样品:

背景

E3 ubiquitin-protein ligase . Mediates 'Lys-63'-linked polyubiquitination and stabilization of the JUN coactivator RNF187 in response to growth factor signaling via the MEK/ERK pathway, thereby regulating JUN transactivation and cellular proliferation . Promotes the TLR4-mediated signaling activation through its E3 ligase domain leading to production of proinflammatory cytokines and type I interferon . Plays also a negative role in the regulation of exogenous cytosolic DNA virus-triggered immune response. Mechanistically, enhances the 'Lys-48'-linked ubiquitination of STING1 leading to its proteasome-dependent degradation .

储存条件

储存条件：储存条件在：-20℃下储存一年, 避免反复冻融.

储存缓冲液：含0.15% ProClin300防腐剂, 100 μg/mL牛血清白蛋白和50%甘油的磷酸盐缓冲液.

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