Myeloid leukemia factor (MLF) proteins typically demonstrate highest levels of expression in testis, ovary, skeletal muscle, heart, kidney and colon tissues, and lower levels of expression in spleen, thymus, and peripheral blood leukocytes. MLF proteins play a role in normal hemopoietic differentiation as well as in erythroid/myeloid lineage switching. MLF2 is a ubiquitously expressed, 248-amino acid protein which shares 40% sequence identity with myeloid leukemia factor 1 (MLF1).