Anti-SIX3 兔多克隆抗体-转录因子-科普欣生物 Cookbio 抗体|仪器|耗材|试剂-武汉科普欣生物科技有限公司

Anti-SIX3 兔多克隆抗体

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￥1900

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货号： K1344445-100

预测分子量： 36 kDa

观测分子量： 37 kDa

别名： HPE2, Sine oculis homeobox homolog 3, SIX homeobox 3

应用 | 种属

WB H,M

规格：

100 μL 50 μL

产品描述
应用
背景
储存条件
图像

产品信息

蛋白质全称	同源框蛋白SIX3
别名	HPE2, Sine oculis homeobox homolog 3, SIX homeobox 3
Uniprot ID	Q62233
免疫原	KLH偶联的小鼠Six3合成肽
抗体亚型	IgG
纯化方式	亲和纯化
预测分子量./观测分子量.	36 kDa / 37 kDa

应用

WB 免疫印迹

物种:人, 小鼠

稀释比:1: 100-1: 300

阳性样品:

背景

Transcriptional regulator which can act as both a transcriptional repressor and activator by binding a ATTA homeodomain core recognition sequence on these target genes. During forebrain development represses WNT1 expression allowing zona limitans intrathalamica formation and thereby ensuring proper anterio-posterior patterning of the diencephalon and formation of the rostral diencephalon . Acts as a direct upstream activator of SHH expression in the rostral diencephalon ventral midline and that in turn SHH maintains its expression . In addition, Six3 activity is required for the formation of the telencephalon.Acts on the proliferation and differentiation of neural progenitor cells through activating transcription of CCND1 AND CCND2 .

储存条件

储存条件：-20℃下储存一年, 避免反复冻融.

储存缓冲液：含0.15% ProClin300防腐剂, 100 μg/mL牛血清白蛋白和50%甘油的磷酸盐缓冲液.

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