Anti-E2F1 兔多克隆抗体-肿瘤标志物-科普欣生物 Cookbio 抗体|仪器|耗材|试剂-武汉科普欣生物科技有限公司

Anti-E2F1 兔多克隆抗体

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￥1900

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货号： K1346548-100

预测分子量： 46 kDa

观测分子量： 55-60 kDa

别名： E2F1, E2F-1, RBAP1, RBBP3, RBP3, E2F transcription factor 1

应用 | 种属

WB H

规格：

100 μL 50 μL

产品描述
应用
背景
储存条件
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产品信息

蛋白质全称	转录因子E2F1
别名	E2F1, E2F-1, RBAP1, RBBP3, RBP3, E2F transcription factor 1
Uniprot ID	Q61501
免疫原	KLH偶联的小鼠E2F1合成肽
抗体亚型	IgG
纯化方式	亲和纯化
预测分子量./观测分子量.	46 kDa / 55-60 kDa

应用

WB 免疫印迹

物种:人

稀释比:1: 300-1: 400

阳性样品:

背景

Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F1 binds preferentially RB1 in a cell-cycle dependent manner. It can mediate both cell proliferation and TP53/p53-dependent apoptosis. Blocks adipocyte differentiation by binding to specific promoters repressing CEBPA binding to its target gene promoters Positively regulates transcription of RRP1B.

储存条件

储存条件：-20℃下储存一年, 避免反复冻融.

储存缓冲液：含0.15% ProClin300防腐剂, 100 μg/mL牛血清白蛋白和50%甘油的磷酸盐缓冲液.

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